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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf6e1e8f50557ac053ff6133ef1e8a384836baa66b9b6d29211a17489b19d610' 
  AND token = 'MDz5pV6wwIw/LU16JFatGjIjWRnjtFNvVJ/hRjs6HtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}