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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70e5caafb813f701a02e5445572ad69356f4dd3a431dda56b92b9ed9f5e7e0da' 
  AND token = 'mVTbHQm/UXCpw8ZqZUcTaxQLs2uhRA4L9fyzTMk7aqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}