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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd27cc34a27bb32f440d9e170786a3e8f2002df7566bea859bfb49a8071ffc049' 
  AND token = 'LEu5XcNwN07F7eEUDzig3wu1gmhpNVAJi3qf7k6T53I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}