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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29b99a48d43162ea081ad2005bd6ee49ecb991997134acc38ce8c73cc5e19ab7' 
  AND token = 'ptLqb7zEv7C2ugeeXUxtUVC8KW1iB4O2vYfV6d9Aoxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}