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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4f64dbff5651b3c7db9948ecc6f78e129b60d929cc30dc4da7e63abb22217d4' 
  AND token = 't/+xf29tfhp8yISCVkUsO4zIhJKdhD0B5r0rBqzrR0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}