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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '784dd332921cc19464355b83b4e29a60e4e26753aaf152ec0a4963fc15f16e08' 
  AND token = '8rWsV+IPwRWB42AOE3apoVmI3aQD13XgQdMyWvj2NuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}