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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a49c35372b0fa90405fd9dd704eb55e3bf3131f9eeaf8d8eae86c785c1100a9' 
  AND token = '+5PAF9gB+5OwdfLWrt30YGyraC3BURMdR9NJtAQZxzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}