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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '355a75fb59d988a09fb08fd202dc11f1f314dea18e0d28cae8c58a9f219328c2' 
  AND token = 'nzNchUMkcTCrVLJ5gWP6S7OMCVvsUYzudh77rhz40Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}