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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f657d65fbe2a516ef90578e3db98d39d113678f7d41851f373084e1d761689f' 
  AND token = '3B6OHAXrkZqpMJg4vkovOW7DQXpHEH55+hTyLNLf2bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}