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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45516fdcb81590ce1e2dbb731bf155c3427e13a0ec5522499795b3cc41d55b77' 
  AND token = 'mH4T/C88d5OjEOOEbp3R4nqb269VFSSUPO07VvegPgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}