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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6cd90239797184715924df9123cb43c4d2a53a5aac4974307e8285f3d099019' 
  AND token = 'FU+uSUpei8ze+qFG0Kacv6JsXhK57Rw9GSkU0h4VINQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}