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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bbe8f9e487744c8aa58baf64f0499865f8911ecc2d0c497f12de72c71c16a04' 
  AND token = '0S/VVuxDzRI4HWyH6L4tUfJuTRZoIMkHHNRwjswv8Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}