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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca286de1e641cf84aed06ddc3a13816797a937e5a97eb99920d5d0f8cb829572' 
  AND token = 'KN77cx+K/Jt0S2uxrfsy5m2fcO2PPXia2OvNz6V4qs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}