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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ced7e94927006d5b3c68c089684c03e559b04346e855d3c40deac51f2ca19396' 
  AND token = '+BGgzdtj0qK89sypIT+eTY/DILY52O13/UyAs5c2FCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}