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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f20cc2da4050b463ae98c051ddfc46efe9aa88874332c13fd9e547ce7814cf' 
  AND token = 'EFDXMzkpdSuSmC/CDN3pXqxZbb+LoFoXm18iIo/4wn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}