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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71bd81edd1308883b7b33edebb4e5b74079285b3dfec8b163963af96f617b5c6' 
  AND token = 'GIQlBUfxl7j0rvdV1e0vo+P3/JsGezez5bW+S2gt1HI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}