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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52d4b75c3d3ef8ad99b886c4d82150a88f4d2eca6151b0794771e204b9424bdb' 
  AND token = 'zSBL8yL6FIUOU9eDUM1nflYs2KKaTLfIrWjV3OiTj0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}