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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac613b43817684a430d4de6dff2bf71e5e09b7a6da3bc2e8e9f1b51343fbcfb' 
  AND token = '0B6QnkIa8bQb0k/xOX7mUhFINi1SIOerMCiyvJYdf6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}