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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ac8363de447f879ee1bed0982a3f90b02acb4b7c9f80bac219e4a3fe603728a' 
  AND token = 'KxvJ+tp2L8FQc1FrkgMdNoBd2hQz/x81F8J89MfFnCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}