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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca0ce38854dea16f3e3a18f5cd6ae18b1b9e3e52978e25d0aca3e6d366f3183a' 
  AND token = 'm3AHYRfvVC46N5dOquAXYnUZ7zy0Cg4oQUtMF/D0WsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}