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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7b9d6a0e038e0f716acacd1a029cf4abfdd2aed621a6efd0e548147e0b7b477' 
  AND token = 'C1LK7w41SUcNbUMqK4Mz9GAgdUlduXTp4G4rdNQdUSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}