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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b2593c947d4ce0e77c41e8dd32ee1ca8b331f1093043b0d876d7bb09dae0668' 
  AND token = '5cF4wPo1H7dRi252X060OkTeVxtXVG0serX4xzhAeeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}