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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4686347cbdd56a2d2134db9a4f8620966a1a3b6e975cb740e9c1baa5a19604b2' 
  AND token = 'sKhFOcsOVfuM8B8xvxEDiv3viXF51wqlsP4371iuKaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}