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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b5c14c61ab55d0788caf7264a7ea3196950557ece986eccfe12c501d7742377' 
  AND token = 'syjp0dRZK3V9hVgcCLEpf5JOHsWDTubLu/eiKkqUFq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}