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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7115e085217e3076fdade722474d05883fa146057577a83160f2a9b4d7c50aae' 
  AND token = 'GZKuxw5BCSZlqPrRJk0+jg4L28NpT7RJeEkTp6Emz80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}