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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8163c69740ee6aae6f8080ecd481f1470f03c904b8d7e15c4831e23fc64d59a3' 
  AND token = '8h67sJcH2+v4293z6sV8e1sMqiRDR91imtzmiZwXbyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}