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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee136209d00dfb01b86b5792dbfea98775693f51649887d6cddfa7fd4c7ac950' 
  AND token = 'y9TRfe3In+RHGjE04xtcJBtvOd+8Xq7hcoMgvPlK4ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}