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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e821dc44ec1b56a997007bf430e33ba727adedc6c1c9eacd7da9b76abc2b04' 
  AND token = 'MV25py7OST/7RhT1J1wwgER2bZGH7e4+gJ4GZJC74ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}