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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7078edf87d470b157d0e11395f18bc8f246ee48e430d9e027a94207e012214de' 
  AND token = 'Ztwzdy1tvAM0qCfJYTKguImfl64K52+MQ9sxH8jiU/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}