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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bc5616af3cb355e71e53483331f3af1392a48d801ac36737b5fb9669a3b1754' 
  AND token = '9lPxvNPrQsnaOz7wodsF/zMemVrLGoeTNGlMfr0OYHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}