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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8584fcd0c7e66eed1e19c66dbe9f7fcb17b1213cdbc20b4e27f78f439634fc21' 
  AND token = 'zpOIwmtyjsta4JON2MjI+h/QldRc86YjR8Ni5vlU6I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}