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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86ab1c19d3c249eb62344677f0004012beb47fc7a64d709bd7488a74a8d526fc' 
  AND token = '0u1agFizAYCg/YR0J441HdUnJxWaeQAnFbXU8WDz4Dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}