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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4314f2c3a3f583deb0664cb1d1376ff240f7acbf450557bf4b9e80e4c1dd29b' 
  AND token = 'rdQfMHlYF3REI2elpYCzLgE8Blr6sE4Rp6uT1cZLn4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}