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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caef20fbea4288bf3b0d1aabb8317f7cb74fb578b000cd37babfc92d00debd30' 
  AND token = 'Z6VwE6axMX8t6VLCFnCkPdJqS7zHlVixHe4zm/jBvM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}