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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16b36bde94f7148f5f3dc8a3ec4327b390914b71a0c31df090fd0cb96eb338da' 
  AND token = 'bvDmlQN0i/fsMEHKBY65sn2CwEWSl5rmVNMyZRdClA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}