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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9049d1770ff7fd81a5ddbf0f51d12d77803f2a2d9111b2b7f0cfacd7daa3dbc4' 
  AND token = 'D4FNbI8zxJMVeyV0tsD6gjVtcT68yeZKwQsGW4oaIIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}