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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b16f718f2666f6cb84147e7f8d190fddfda3fe2d156ca72a09eec860e0535e9' 
  AND token = 'Dc3HUcIfDPjo83zZ8JEtkiosFJXU1fHeM19ctf81aAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}