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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '506e1dd3057e604c5891c30b49811573c8761077bdf4cf91866bd461a67f3046' 
  AND token = 'w1X0tgeGoSk70iggNtTq6IBT/BLOZvol95tzUi1y528=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}