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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de1ab818b6a5d42b96b1e439beb71326114cfd2d2dd9665da5f81e6e73f6ba06' 
  AND token = 'c+TL1bsNVL9TqUKzbWHzcMVlLPe7PybCbFhej/mi9Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}