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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d3f46003acb72152224958100bdbf65e8399c68fc9835facd99281d8a10ce12' 
  AND token = '/gwzDFOi18xhBBrbJaA+H5kN74dJN79p3j64ubZ1VIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}