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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '589d3b45c5c5551bbea4e4458839055c8b63d5f50780976d3819e30f76871a09' 
  AND token = 'GIyz8RV8t/4wi+1RKaFs5oZ+Y7/EPkQETiPj5n9mtXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}