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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60f400701a35b71ba57fb667bc21d5975fa8a1281e78f02496d02f3c3e5c06b7' 
  AND token = 'GQOxxrbt1S5R8X04eoi38pHAu3kHMucYjLR2sJwAixk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}