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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf8ea80ab3f8e4e3b96fd238a95641e87a1f440dfdaddd148e5336fc682d0f56' 
  AND token = 'W7/4m9geFtWQ3mrHaBJe6LOxrkCMV8FYsK6qhC0R5x0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}