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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a09d796fecd068b7763cf0b0d997f3fb3dbc127ba69ea54dc0a552c5a5784166' 
  AND token = 'DUtw4KJvKSB1834lTrbnXkRmRTfZPrSVx/xgyE0Xncw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}