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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d24c5dadf41ce0f854d1dcb2dc105fe8e313308dc6d0c975e2740f57eea796b' 
  AND token = 'IrTqe9aqqafDAnZn1q5cI5Du7YBnGJ3AXTQrPlCg13Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}