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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d50b946ff1231f49c4a173183558ed5e2578a09e49f038e18afa1fb60c0674' 
  AND token = 'uW5unh+/XJyelJloA+9cfVAOUK/c1nAhQNAZOY91KGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}