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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3aa6fd0394e35583681b67d8294aa4125dab65a26d457a7a431fea9256be62f' 
  AND token = 'uMBVHoC5GRu2WgjAkd5dZlE0opuDINx9Df8OrZBkDOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}