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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d2b9bce9e6116ea2e81cb954149f71d2167ceb6f15bf559dd4398810e672ae' 
  AND token = 'vHTWPQ5E8Oo4c29nJHSrI7nV3XVEpj9xCxXk9N4yRl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}