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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '146b1a8f31db852c15a1a14cb4b1dd25aba740f9fb31c17383b5d3245f424c23' 
  AND token = 'UMTgPKQ/7KNXEYBprq/r0POIP5kleKHWKk8DBz7mAxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}