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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eb1a2ddefb9b05e79537e32759e8d9284bae4af5d69ddca9124f1e44dbdebf5' 
  AND token = 'ZIgvXTmDYhh8SWpWRIfFBfPRs9VRo11UOdqcMz0TmLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}